This is such a nice question, thanks! I study how the pressure in the eye is controlled so the eye can keep its shape and normal functioning. For 50 years, we thought that the cells that are in charge of draining the liquid that fills the front of the eye (aqueous humour) were not involved in the drainage. But I have recently discovered that this was not true, the cells are very important, and they control how much fluid is drained. Technology has advanced a lot, so, we sometimes have to look back at old science to see if what we thought was true can still be proved. This also shows us that new discoveries might be proven wrong in the future, we only know what we can experiment with current technology. Science evolves!
It is so difficult to pick the most interesting one! But if I have to choose one I chose spinal cord regeneration in the axolotl. I set out to study how the cells that make up the spinal cord regrow a new spinal cord after the axolotl loses its tail and what molecules guide them. I discovered that these cells normally divide very slowly, but they divide 3x quicker during regeneration to make up for the lost tissue! I also found that these cells activate molecular programmes that are used to build the spinal cord in the first place, during embryonic development. So, in a way, axolotls cells go back in time to rebuild the spinal cord as grown-ups!
This is a really good question. For me I really enjoy understanding things on the most fundamental level, so things involving the forces of nature, why reactions happen and weird properties like magnetism are what I have found most interesting.
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