Question: If you take 2 sperm cells with x chromosomes and take out the nuclei from an egg cell, and replace the egg cell nuclei with a nuclei from the sperm cell and then fertilise that egg cell with a sperm cell with a x chromosome – can you make a female/girl? please think about it, i wanna know pleaseee im begging

Andrew Cairns answered on 18 Nov 2011:

This is a very interesting question, and one that there has been debate about. Having developments like this would allow same-sex couples to have children that are biologically both of theirs.

However, there are several issues you might come across in Biology class:

1) Mother nature is very clever, and having female as XX and male as XY means that there always a 50% chance of a boy being conceived and 50% of a girl if Y is dominant:

Cross | X | X |
X | XX | XX |
Y | XY | XY |

But, if you have two XYs:

Cross | X | Y |
X | XX | XY |
Y | XY | YY |

There is a 25% of getting a girl, 50% chance of a boy and 25% of a “YY”.

2) We don’t know if it is possible to have a YY combination and have a healthy baby.