Basically what happens is that when drugs (for example stimulants such as ecstasy) enter the body they cross into the brain. What happens then is they alter two very important chemicals in the brain, serotonin and dopamine. These two chemicals are very important in our body they work a lot on the nervous system (amongst other things). So when you alter these by using drugs it directly effects these chemicals and tells the brain to tell the nerves in your body to do things that normally it wouldn’t.
Given that your brain controls your whole body, you can see why they can be so dangerous.
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