The parasite that causes the most deaths is the plasmodium parasite (technically 5 subspecies), which causes malaria for which there are treatments, but still causes around 600,000 deaths/year. I think Naegleria fowleri is probably the deadliest, anything called brain-eating ameba is something I want to stay away from.
Here’s a video about plasmodium that I helped make for world malaria day.
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