• Question: What led you to your discovery about blood clots?

    Asked by sesquipedalianist to Lorna on 17 Mar 2010 in Categories: .
    • Photo: Lorna Houlihan

      Lorna Houlihan answered on 19 Mar 2010:

      Nice question! So we have a group of people (pic on my profile page) of over 1,500 people born in Scotland in either 1921 or 1936 and on everyone we measured their rate of blood clotting by a test called activated partial thromboplastin time. We also measured around 500,000 genetic variants on these 1,500 people’s DNA. We then did some stats to see if any of the genetic variants were associated to the activated partial thromboplastin time – and they were!! in three different genes. This was a discovery that no one else had found before. What do you think? like more info?

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