Definitely! Many single-cell organisms like amoeba are definitely alive and (like the name suggests) they only have one cell.
One of the features of more complicated organisms is multicellularity – they have lots of cells which work together as tissues. But a single cell is definitely alive.
Some cells like red blood cells don’t have much DNA, though, and they can’t replicate – so maybe those don’t count as living. I’m not sure!
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