• Question: What do you have to take into perspective when developing psychopharmaceutical drugs.

    Asked by Mr.Walter.White to Zoe, Sarah, Elaine, David, Aaron on 13 Nov 2014.
    • Photo: David Foley

      David Foley answered on 13 Nov 2014:


      Very good question. A key challenge for any drug that works in the brain is over coming the “blood-brain barrier”. This special layer of cells is designed to protect the brain from many chemicals, including a lot of drugs. Drugs that do cross it have very different properties in terms of how basic and water soluble they are.

    • Photo: Zoe Roberts

      Zoe Roberts answered on 17 Nov 2014:


      Making drugs that work on a function of the brain is a challenging process. The drug needs to not only make it through standard digestion but it also needs to cross the blood-brain barrier. This barrier stops chemical from getting into the brain and damaging it. Drugs that are made to cross this barrier have to fulfill certain properties to acheive this.

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